Korean Journal of Gastrointestinal Endoscopy 1987;7(1): 39-41.
인환세포암종과의 감별을 요한 위점막내 Russell 소체 함유 형질 세포 침윤 ( Russell Body - Containing Plasma Cell Aggregations Mimiccking Signet Ring Cell Carcinoma of the Stomach )
유은실, 김용일, 김철우, 김우호 (Eun Sil Yu, Yong Il Kim, Chul Woo Kim and Woo Ho Kim)
Abstract
This report presents a case with gastric ulcer whose gastric mucosal biopsy revealed heavy aggregations of Russell body containing plasma cells in the lamina propria and in peptic detritus. A sixty four year old female received an endoscopic examination for currently aggravated peptic ulcer symytoms, It revealed a small round ulcer with nodular margin along the greater curvature of high body, suggesting of early gastric carcinoma. Endoscopic biopsies (two times) confirmed heavy collections of Russell body-containing plasma cells which were once misinterpreted as signet ring cell carcinoma. Immonohistochemically they were strongly positive to both kappa and lambda light chains by pgtroxidase-antiperoxidase method. Each infiltrated cell contained one or more refractile intracytoplasmic eosinophilic globules, bcing associated with extracellular ones and heavy matare lympho-plasma cell infiltration. Differential diagnosis from neoplastic signet ring cells in endoscopic biopsy was diseussed.
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