Korean Journal of Gastrointestinal Endoscopy 2004;28(2): 71-75.
불명확한 원발부위의 전이성 위 악성 흑색종의 내시경적 진단 2예
류재성†·오혜주†·허진욱·김지연·이지영·윤병철·박무인·박선자·장희경*·구자영
고신대학교 의과대학 내과학교실, *해부병리학교실, †대동병원 내과
Two Cases of Endoscopically Diagnosed Gastric Metastatic Malignant Melanoma of
Jae Seong Ryu, M.D.†, Hyae Ju Oh, M.D.†, Jin Wuk Hur, M.D., Jee Yeon Kim, M.D., Jee
Departments of Internal Medicine and *Pathology, Kosin University College of Medicine,
Abstract
Although malignant melanoma involving the stomach is commonly mentioned in association
with autopsies, endoscopic experience in this gastric malignancy is still limited, and few cases have
been illustrated in the literature. This clinical condition is even rarer in Asians who are much less
vulnerable to malignant melanoma than Caucasians. We experienced two cases of gastric metastases of
malignant melanoma which presented as indigestion and epigastric pain. In the first case, a
75-year-old man visited because of indigestion persisting for 2 months. He had a history of multiple
gastric ulcer and was treated at a local medical center, but symptoms did not improved. Endoscopic
finding revealed multiple and elevated lesions with central black pigmented bases. In the second case,
a 47-year-old man visited because of epigastric soreness and intermittent pain for 1 month. Metastatic
melanoma in the stomach was noticed by endoscopic examination. Both patients had multiple
metastatic lesions in the liver, thyroid, and brain. These two cases were diagnosed as having metastatic
malignant melanoma in the stomach of unknown origin. Therefore, we report these cases with a brief
review of the related literature. (Korean J Gastrointest Endosc 2004;28:7175)