Korean J Gastrointest Endosc > Volume 28(6); 2004 > Article
Korean Journal of Gastrointestinal Endoscopy 2004;28(6): 277-283.
간경변증 환자에서 동반되는 십이지장 병변에 대한 임상적 고찰
김진배·한동수·이항락·김종표·박준용·이오영·손주현·최호순·함준수
한양대학교 의과대학 내과학교실, 구리병원
Clinical Features of Duodenopathy Associated with Liver Cirrhosis
Jin Bae Kim, M.D., Dong Soo Han, M.D., Hang Lak Lee, M.D., Jong Pyo Kim, M.D., Joon Yong Park, M.D.,Oh Young Lee, M.D., Joo Hyun Sohn, M.D., Ho Soon Choi, M.D. and Joon Soo Hahm, M.D.
Department of Internal Medicine, Hanyang University College of Medicine, Guri, Korea
Abstract

Background/Aims:
Congestive duodenopathy could be associated with liver cirrhosis with portal hypertension. The aims of this study were to assess the incidence of duodenopathy and to evaluate the relationship between duodenopathy and the presence of esophageal varices and portal hypertensive gastropathy in cirrhotic patients.
Methods:
A total of 56 patients with liver cirrhosis and 481 controls were taken upper endoscopic examination.
Results:
Prevalence of duodenopathy was significantly higher in the liver cirrhosis group (26.8%) compared to the control group (6.9%), although positive rate of Helicobacter pylori was significantly lower in the liver cirrhosis group. Duodenal erosions in cirrhotic patients were predominately located in 2nd portion of duodenum compared to contol group and tended to be circular or linear along the Kerck's ring. Vascular congestion was evident in 5 of the 10 cases. Presence of duodenal lesions had no relationship with the size and extent of esophageal varices and congestive gastropathy.
Conclusions:
Although histology of duodenopathy tends to show vascular congestion in patients with liver cirrhosis, few clinical markers of portal hypertension support them. Therefore, further studies including endoscopic ultrasonogram are needed to demonstrate the pathogenesis of the duodenal lesions in patients with liver cirrhosis. (Korean J Gastrointest Endosc 2004;28:277⁣283)
Key Words: Liver cirrhosis, Duodenopathy, Congestive gastropathy, Congestive duodenopathy, Portal hypertension
주요어: 간경변증, 십이지장 병증, 울혈성 위병증, 울혈성 십이지장 병증, 문맥압 항진증
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