십이지장 이소성 위 점막의 내시경적 특징 |
송해정·이지현·정인섭·홍수진·유창범·김진오· 조주영·이준성·이문성·심찬섭·김부성·진소영* |
순천향대학교 의과대학 내과학교실, 소화기연구소, *병리학교실 |
Endoscopic Features of Ectopic Gastric Mucosa in the Duodenum |
Hae Jung Song, M.D., Ji Hyun Lee, M.D., In Seop Jung, M.D., Su Jin Hong, M.D., Chang Beom Ryu, M.D., Jin Oh Kim, M.D., Joo Young Cho, M.D., Joon Seong Lee, M.D., Moon Sung Lee, M.D., Chan Sup Shim, M.D., Boo Sung Kim, M.D. and So Young Jin, M.D.* |
Institute for Digestive Research, Digestive Disease Center, *Department of Pathology, Soon Chun Hyang University College of Medicine, Seoul, Korea |
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Abstract |
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Background/Aims: The origin of gastric mucosa outside of the stomach may be developmental (heterotopic gastric mucosa) or acquired (gastric metaplasia). The aim of this study was to evaluate the endoscopic features, according to the subtypes, of the gastric mucosa outside the stomach in the duodenum. Methods: A total of 30 consecutive patients who underwent esophagogastroduodenoscopy from January 2002 to August 2004 and who were confirmed histopathologically as having gastric mucosa outside the stomach were retrospectively analyzed. Twenty three patients were males and seven were females. Results: Nine patients had heterotopic gastric mucosa and 21 patients had gastric metaplasia. Seven patients with heterotopic gastric mucosa were asymptomatic and 2 patients had dyspepsia, whereas 21 patients with gastric metaplasia had dyspepsia. The dyspepsia rate showed a significant difference between the two groups (p<0.001). Endoscopically, the appearance of the heterotopic gastric mucosa tended to resemble area gastricae (p=0.08). However, there were no statistically differences between the two groups for the endoscopic features of the duodenum. Other abnormal lesions in stomach and duodenum appeared more frequently in the gastric metaplasia than in the heterotopic gastric mucosa (p=0.004, p<0.001). There was no difference in the prevalence of Helicobacter pylori infection between the two groups. Conclusions: There are no specific endoscopic findings to differentiate heterotopic gastric mucosa from gastric metaplasia. The presence of symptoms and the associated gastroduodenal inflammatory lesions were more prominent in the gastric metaplasia compared with the heterotopic gastric mucosa. (Korean J Gastrointest Endosc 2006;32:246252) |
Key Words:
Duodenum, Heterotopic gastric mucosa, Gastric metaplasia |
주요어:
십이지장, 발달형 이소성 위 점막, 획득형 이소성 위 점막 |
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