Korean J Gastrointest Endosc > Volume 34(4); 2007 > Article
Korean Journal of Gastrointestinal Endoscopy 2007;34(4): 193-199.
소아 크론병의 임상적 특징과 경과
이나영·박재홍*
부산성모병원 소아과, *부산대학교 의과대학 소아과학교실
Clinical Features and Course of Crohn Disease in Children
Na Young Lee, M.D. and Jae Hong Park, M.D.*
Department of Pediatrics, Busan St. Mary's Medical Center, *Pusan National University Hospital, Busan, Korea
Abstract

Background/Aims:
The aim of this study was to evaluate the clinical features and course of Crohn disease (CD) in children.
Methods:
The medical records of 30 patients diagnosed with CD between January 1996 and December 2005 were reviewed retrospectively.
Results:
The actual number of newly diagnosed patients with CD has increased during the 8-year period. The male/female ratio was 2:1 and the mean age at diagnosis was 10.6⁑4.3 years. The major symptoms of CD at diagnosis were abdominal pain (79.2%), weight loss (54.2%), perianal lesion (54.2%), diarrhea (45.8%), hematochezia (41.7%), anemia (29.2%), and fever (23.3%). The disease location of CD was the small bowel in 33.3%, the large bowel in 12.5% and both the small and large bowel in 54.2%. Granuloma was found in 54.2% of patients. The relapse rate of CD in the group with a higher pediatric Crohn disease activity index (PCDAI) at diagnosis (≥30) was higher than in the group with a lower PCDAI (<30). The cumulative relapse rates of the patients with granuloma were 30.2% within 1 year and 53.8% within 5 years after the diagnosis.
Conclusions:
The incidence of CD in children appears to be increasing. Granuloma formation and a higher score of the PCDAI are associated with a more severe disease course. Pediatric CD may have a somewhat different clinical presentation from older-onset CD. (Korean J Gastrointest Endosc 2007;34:193⁣199)
Key Words: Crohn disease, Children
주요어: 크론병, 소아
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
CrossRef TDM  CrossRef TDM
  E-Mail
Share:      
METRICS
1,389
View
20
Download
Related articles
Clinical Features and Predictors of Dysplasia in Proximal Sessile Serrated Lesions  2021 July;54(4)
Clinical Features of Iatrogenic Mallory-Weiss Syndrome  2009 August;39(2)
Clinical Features and Prognostic Factors in Ischemic Colitis  2008 June;36(6)
Clinical Features of Ischemic Colitis: A Comparision with Colonoscopic Findings  2006 September;33(3)
Clinical Features of Gastrointestinal Bleeding in Patients with Chronic Renal Failure  2006 June;32(6)
Editorial Office
Korean Society of Gastrointestinal Endoscopy
#817, 156 Yanghwa-ro(LG Palace, Donggyo-dong), Mapo-gu, Seoul, 04050, Korea
TEL: +82-2-335-1552   FAX: +82-2-335-2690    E-mail: ce@kams.or.kr
Copyright © Korean Society of Gastrointestinal Endoscopy.                 Developed in M2PI
Close layer