Korean Journal of Gastrointestinal Endoscopy 2007;35(2): 68-73.
대장암 선별검사로 시행한 분변잠혈반응검사의 의의
권정현·최명규·서정필·장재혁·남관우·박호성·백창렬·박재명·조유경·이인석·김상우·정인식
가톨릭대학교 의과대학 내과학교실
The Significance of Fecal Occult Blood Testing to Screen for Colon Cancer
Jung Hyun Kwon, M.D., Myung Gyu Choi, M.D., Jung Pil Suh, M.D., Jae Hyuck Chang, M.D., Kwan Woo Nam, M.D., Ho Sung Park, M.D., Chang Nyol Paik, M.D., Jae Myung Park, M.D., Yu Kyung Cho, M.D., In Seok Lee, M.D., Sang Woo Kim, M.D. and In Sik Chung, M.D.
Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Abstract
Background/Aims: We investigated the efficacy of the fecal occult blood test (FOBT) as a colon cancer screening tool in a tertiary hospital setting. Methods: This retrospective study analyzed patients who underwent routine check- ups at Kang-Nam St. Mary's Hospital Health Promotion Center from January 2004 to April 2005. All the subjects were encouraged to submit stool for a FOBT, while performing a double contrast barium enema (DCBE) was optional for those who wanted colon examination. Colonoscopy was performed if the FOBT or DCBE results were abnormal or if the patients had bowel symptoms. Results: The FOBT was performed in 8,198 of 10,182 patients (80.5%) who underwent routine check-ups. The overall positive rate of FOBT was 149 of 8,198 (1.8%) and this increased with age (p＜0.05). Colonoscopy and/or DCBE was performed in 33 of 149 patients (22.1%) in the FOBT positive group. Colon cancer and polyp were diagnosed 2 (6.1%) and 7 (21.2%) patients, respectively, in the FOBT positive group, whereas colon cancer and polyp were diagnosed in 3 (0.5%) and 102 (15.7%) patients, respectively, in the FOBT negative group. The sensitivity and specificity of the FOBT for colon cancer was 40% and 95.4%, respectively. Conclusions: Although it had low sensitivity, the FOBT was a useful screening tool for detecting colon cancer in a tertiary hospital setting.
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