| Immunoglobulin G4 면역조직화학 염색으로 진단된 자가면역성 췌장염 1예 |
| 문태건·이규택·김회진·이준상·하정수·강 풍·이종균·김재준·이종철·장기택* |
| 성균관대학교 의과대학 삼성서울병원 내과학교실, *병리학교실 |
| A Case of Autoimmune Pancreatitis Diagnosed by Immunohistochemical Staining of IgG4 |
| Tae Gun Moon, M.D., Kyu Taek Lee, M.D., Hoi Jin Kim, M.D., June Sang Lee, M.D., Jung Su Ha, M.D., Pung Kang, M.D., Jong Kyun Lee, M.D., Jae J. Kim, M.D., Jong Chul Rhee, M.D. and Kee Taek Jang, M.D.* |
| Departments of Internal Medicine, *Pathology, Sungkyunkwan University College of Medicine, Samsung Medical Center, Seoul, Korea |
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| Abstract |
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Autoimmune pancreatitis is a distinct entity with characteristic morphological, histological and clinical features. Since the first report in 1961, there have been many reports on autoantibodies associated with autoimmune pancreatitis. Lymphoplasmacytic infiltration with fibrosis is the characteristic histological feature of autoimmune pancreatitis. Elevation of immunoglobulin G4 (IgG4), a subtype of IgG, can be seen in autoimmune pancreatitis. A few reports of autoimmune pancreatitis based on immunostaining of IgG4 have been published, but no reports have been published in Korea. We present here the first report of autoimmune pancreatitis, based on an increased serum IgG4 level and plasma cell infiltration that showed IgG4 positivity by immunohistochemical staining of the major papilla. (Korean J Gastrointest Endosc 2007;35:205-209) |
| Key Words:
Autoimmune pancreatitis, Immunoglobulin G4 |
| 주요어:
자가면역성 췌장염, Immunoglobulin G4 |
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