Korean J Gastrointest Endosc > Volume 35(4); 2007 > Article
Korean Journal of Gastrointestinal Endoscopy 2007;35(4): 254-257.
제1형 신경섬유종증에 동반된 위장관간질종양에 의한 십이지장출혈
서승오ㆍ오효정ㆍ김기훈ㆍ최창수ㆍ서검석ㆍ김태현ㆍ윤기중*ㆍ최석채
원광대학교 의과대학 내과학교실, 소화기질환연구소, *병리학교실
A Case of Duodenal GIST Accompanied with Neurofibromatosis-1, Presenting with Gastrointestinal Bleeding
Sung O Seo, M.D., Hyo Jung Oh, M.D., Ki Hoon Kim, M.D., Chang Soo Choi, M.D., Geom Seog Seo, M.D., Tae Hyeon Kim, M.D., Ki Jung Yun, M.D.* and Suck Chei Choi, M.D.
Department of Internal Medicine and Digestive Disease Research Institute, *Department of Pathology, WonKwang University College of Medicine, Iksan, Korea
Abstract
Gastrointestinal stroma tumors (GISTs) are CD117- positive primary mesenchymal tumors of the gastrointestinal tract and are noted to have a possible non-random association with neurofibromatosis-1 (NF-1, Von Recklinghausen disease). We report a case of a duodenal GIST presenting with gastrointestinal bleeding in a 74-year-old female, and this condition was accompanied with NF-1. A upper gastrointestinal endoscopy and abdominal computed tomography scan revealed several submucosal tumors in the duodenum, jejunum and ileum. Histological and immunohistochemical studies on the surgical resection specimen revealed gastrointestinal stromal tumors of an uncommitted type. The patient was treated with local excision of the tumors and is now in a favorable state. (Korean J Gastrointest Endosc 2007;35:254-257)
Key Words: Gastrointestinal stromal tumor (GIST), Neurofibromatosis-1, Duodenum, Gastrointestinal bleeding
주요어: 위장관간질종양, 제1형 신경섬유종증, 십이지장, 상부위장관 출혈
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