Korean J Gastrointest Endosc > Volume 36(3); 2008 > Article
Korean Journal of Gastrointestinal Endoscopy 2008;36(3): 138-144.
Sodium Phosphate 용액의 내시경하 주입 시 대장내시경 전처치 효과
고신대학교 의과대학 내과학교실
Endoscope-guide Infusion of Sodium Phosphate: A Novel Bowel Cleansing Method, Efficacy and Safety Comparisons with Polyethylene Glycol
Kyu-Jong Kim, M.D., Seun Ja Park, M.D., Eun Kyung Shin, M.D., Jun Young Song, M.D., Do Hyun Kim, M.D., Sung Eun Kim, M.D., Won Moon, M.D. and Moo In Park, M.D.
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea

Single full-dose oral sodium phosphate (NaP) on the examination day instead of a conventional divided-dose has been used in some patients to reduce burdens and sleep disturbance caused by bowel movement. However, this treatment may be inconvenient to some patients who are adversely affected by the full dose or its-related symptoms. This study compared the quality of bowel preparation, side effects, and patient's acceptance after a full-dose of NaP into the duodenum under an endoscopic examination and with those from conventional polyethylene glycol (PEG).
A total of 60 admitted patients receiving both endoscopy and colonoscopy each day were divided randomly into two groups and given either PEG 4 L (n=33) or an endoscopic infusion of NaP 90 mL (n=27). Before and after the bowel preparation and 1 day later, the blood pressure, body weight, and serum biochemical parameters were measured. In addition, a detailed questionnaire was used to assess the patient's side effects. The quality of bowel cleansing was assessed by a single endoscopist who was blinded to the type of preparation used.
Although changes in the serum biochemical parameters (phosphate: increase, potassium: decrease) were observed in the NaP group, all were normalized after 1 day without side effects. There were significant difference in symptoms after the preparation, such as vomiting, but this was not serious. The suction volume was significantly lower in the NaP group.
A duodenal infusion of NaP might be used as a new bowel cleansing method in patients having trouble with other procedures. (Korean J Gastrointest Endosc 2008;36:138-144)
Key Words: Bowel preparation, Sodium hosphate, Duodenum, Endoscopic infusion
주요어: 대장내시경, 전처치, Sodium phosphate, 내시경하 주입
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