Korean J Gastrointest Endosc > Volume 37(6); 2008 > Article
Korean Journal of Gastrointestinal Endoscopy 2008;37(6): 403-408.
일반 상부위장관 내시경의 전처치로서 Cimetropium Bromide의 유용성에 관한 연구
한림대학교 의과대학 내과학교실
The Efficacy of Cimetropium Bromide as a Premedication before Esophagogastroduodenoscopy
Jue Yong Lee, M.D., Sung Jung Kim, M.D., Chang Soon Choi, M.D., Young Mook Kim, M.D., Hyun Joo Jeong, M.D., Jung Eun Lee, M.D., Gwang Ho Baik, M.D., Jin Bong Kim, M.D. and Dong Joon Kim, M.D.
Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea

Cimetropium bromide has been used widely as a premedication for endoscopy; however, there are no subjective data pertaining to the effects of cimetropum bromide as a premedication. Thus, the current study was undertaken to compare the effects of cimetropum bromide with placebo as a premedication for esophagogastroduodenoscopy (EGD).
Two hundred ninety-nine consecutive outpatients who had undergone EGD were enrolled in this study. Thirty minutes before EGD, the patients were randomly given an intramuscular injection of cimetropium bromide (5 mg) or saline using a placebo-controlled, double-blind, randomized technique. Immediately after EGD, all the patients and endoscopists were requested to fill out the questionnaire form.
One-hundred patients were injected with cimetropium bromide and 150 patients were injected with placebo. There was no statistically significant difference in the degree of residual gastric secretions, the peristaltic activity detected by endoscopists, and the comfort experienced by the patients in each study group.
The intramuscular injection of cimetropium bromide (5 mg) as a premedication for EGD was not significantly superior to placebo, at least with respect to subjective parameters, in spite of its broad use. (Korean J Gastrointest Endosc 2008;37:403-408)
Key Words: Antispasmodics, Cimetropium bromide, Esophagogastroduodenoscopy, Premedication
주요어: Cimetropium bromide, 진경제, 상부 위장관 내시경, 전처치
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