Korean J Gastrointest Endosc > Volume 41(6); 2010 > Article
Korean Journal of Gastrointestinal Endoscopy 2010;41(6): 355-359.
위암에 동반된 원발성 융모막암종과 간세포양암종
이수윤ㆍ문희석ㆍ김의식ㆍ김윤정ㆍ고평곤ㆍ이병석ㆍ정현용ㆍ이헌영
충남대학교 의과대학 내과학교실
A Case of Gastric Undifferentiated Carcinoma with Choriocarcinomatous and Hepatoid Carcinomatous Differentiation
Su Youn Lee, M.D., Hee Seok Moon, M.D., Eui Sik Kim, M.D., Yun Jeung Kim, M.D., Pyung Gohn Goh, M.D., Byung Seok Lee, M.D., Hyun Yong Jeong, M.D. and Heon Young Lee, M.D.
Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea
Abstract
Here we report a case of a patient with gastric undifferentiated carcinoma associated with choriocarcinomatous and hepatoid carcinomatous differentiation. A 62-year-old man was referred after a healthcare screening gastroscopy. Gastroscopy revealed an approximately 3×3 cm ulcerofungating mass in the posterior wall of the antrum. Biopsy results revealed a moderately differentiated adenocarcinoma. The initial serum Ձ-FP levels were above 350 ng/mL. An abdominal CT scan revealed focal wall thickening along the greater curvature of the gastric antrum, with perigastric fat invasion and enlarged multiple perigastric lymph nodes. He underwent a palliative radical subtotal gastrectomy and gastroduodenostomy with dissection of the enlarged lymph nodes. Postsurgical histological examination revealed an undifferentiated carcinoma associated with choriocarcinomatous and hepatoid carcinomatous differentiation. Immunohistochemical staining revealed that the tumor cells were positive for human chorionic gonadotropin (hCG), Ձ-FP, and anti-hepatocyte antibody. (Korean J Gastrointest Endosc 2010;41:355-359)
Key Words: Gastric undifferentiated carcinoma, Hepatoid carcinoma, Choriocarcinoma
주요어: 위미분화선암, 간세포양암종, 융모막암종
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