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Video of Issue Exploratory application of endoscopic ultrasound-guided sclerotherapy in right renal cysts
Zhenyun Gongorcid, Jialiang Huangorcid, Wei Wuorcid, Liming Xuorcid, Duanmin Huorcid, Guilian Chengorcid

DOI: https://doi.org/10.5946/ce.2025.034
Published online: May 7, 2025

Department of Gastroenterology, Second Affiliated Hospital of Soochow University, Suzhou, China

Correspondence: Guilian Cheng Department of Gastroenterology, Second Affiliated Hospital of Soochow University, 1055 Sanxiang Road, Suzhou, Jiangsu, China E-mail: 854235202@qq.com
• Received: January 30, 2025   • Revised: February 4, 2025   • Accepted: February 5, 2025

© 2025 Korean Society of Gastrointestinal Endoscopy

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Simple renal cysts require intervention when they exceed 4 cm or cause compressive symptoms.1 Although percutaneous aspiration with sclerotherapy is commonly used, cysts in the upper pole of the kidney pose challenges because of the lack of a safe pathway.2 Endoscopic ultrasonography (EUS)-guided sclerotherapy is a viable option for left renal cysts.3 The right kidney, which is slightly lower than the left kidney, is more difficult to access.
We report the case of a 35-year-old male with a 50 mm×51 mm right renal cyst causing persistent flank pain. Computed tomography revealed that the cyst was located at the upper pole of the right kidney and was obscured by the ribs, making percutaneous puncture difficult (Fig. 1). However, its proximity to the duodenum enabled EUS-guided sclerotherapy. Using EUS, the cyst was visualized posteriorly to the gastric body and punctured through the duodenal bulb using a 22-gauge needle (Fig. 2). Aspiration was initiated with low and gradually increasing negative pressure until the cyst collapsed completely. Finally, lauromacrogol, equivalent to one-third of the aspirated cyst fluid volume, was injected into the cyst cavity (Video 1). After the procedure, the patient received antibiotic therapy for 2 days, and no adverse events occurred.
Although left renal cysts are often incidentally observed during EUS evaluations of the pancreas, right renal cysts are less accessible. However, lesions in the upper pole of the right kidney, particularly those exceeding 5 cm, are easier to detect (either posterior to the gastric body or in the duodenal bulb) and puncture (via the duodenal bulb) (Fig. 3).
To the best of our knowledge, this is the first report of the application of this technique to treat right renal cysts. Our experience with five successful cases of EUS-guided sclerotherapy for right renal cysts (Table 1) demonstrates its safety and effectiveness as an alternative to percutaneous approaches, expanding possibilities for renal and urological interventions.
Video 1. Procedure of endoscopic ultrasound-guided sclerotherapy in the right renal cyst.
A video related to this article can be found online at https://doi.org/10.5946/ce.2025.034.
Fig. 1.
Computed tomography image showing a 50 mm×51 mm cyst (asterisk) in the right kidney, located at the upper pole and obscured by the ribs.
ce-2025-034f1.jpg
Fig. 2.
Endoscopic ultrasonography probe positioned in the duodenal bulb; the cyst was clearly visualized and punctured using a 22-gauge needle.
ce-2025-034f2.jpg
Fig. 3.
Large lesions in the upper pole of the right kidney can be detected either posterior to the gastric body or in the duodenal bulb and punctured through the duodenal bulb.
ce-2025-034f3.jpg
Table 1.
Five cases of endoscopic ultrasound-guided sclerotherapy for right renal cyst
Sex Age (yr) Size of cyst before procedure (mm) Size of cyst after procedure (mm) Cystic fluid volume (mL) Lauromacrogol volume (mL) FNA needle
Male 46 51×50 15×10 75 15 22-G
Male 51 70×60 20×15 120 24 19-G
Male 35 52×41 15×10 60 12 19-G
Male 55 80×70 24×20 150 30 19-G
Female 65 50×50 12×11 50 10 22-G

FNA, fine-needle aspiration.

  • 1. Eissa A, El Sherbiny A, Martorana E, et al. Non-conservative management of simple renal cysts in adults: a comprehensive review of literature. Minerva Urol Nefrol 2018;70:179–192.ArticlePubMed
  • 2. Piccirilli A, Romantini F, Saldutto P, et al. Endoscopic ultrasound-guided trans-duodenal biopsy of a renal mass: Case report and literature review. Urol Case Rep 2020;31:101203.ArticlePubMedPMC
  • 3. Wu W, Zhang Y, Hu D, Song K. EUS-guided sclerotherapy as a new therapy for renal cyst (with video). Gastrointest Endosc 2022;95:587–588.ArticlePubMed

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      Related articles
      Exploratory application of endoscopic ultrasound-guided sclerotherapy in right renal cysts
      Image Image Image
      Fig. 1. Computed tomography image showing a 50 mm×51 mm cyst (asterisk) in the right kidney, located at the upper pole and obscured by the ribs.
      Fig. 2. Endoscopic ultrasonography probe positioned in the duodenal bulb; the cyst was clearly visualized and punctured using a 22-gauge needle.
      Fig. 3. Large lesions in the upper pole of the right kidney can be detected either posterior to the gastric body or in the duodenal bulb and punctured through the duodenal bulb.
      Exploratory application of endoscopic ultrasound-guided sclerotherapy in right renal cysts
      Sex Age (yr) Size of cyst before procedure (mm) Size of cyst after procedure (mm) Cystic fluid volume (mL) Lauromacrogol volume (mL) FNA needle
      Male 46 51×50 15×10 75 15 22-G
      Male 51 70×60 20×15 120 24 19-G
      Male 35 52×41 15×10 60 12 19-G
      Male 55 80×70 24×20 150 30 19-G
      Female 65 50×50 12×11 50 10 22-G
      Table 1. Five cases of endoscopic ultrasound-guided sclerotherapy for right renal cyst

      FNA, fine-needle aspiration.


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