Korean Journal of Gastrointestinal Endoscopy 1998;18(3): 417-425.
증례 : 식도 위장관 ; 호산구성 장염으로 나타난 과호산구 증후군 1예 ( Case Reports : Esophagus , Stomach & Intestine ; A Case of Eosinophilic Colitis as a Complication of the Hypereosinophilic Syndrome )
정혜경, 정성애, 이한주, 이선영 (Hye Kyung Jung, Sung Ae Jung, Han Chu Lee and Sun Young Yi)
Abstract
The hypereosinophilic syndrome (HES) is a leukoproliferative disorder, marked by a sustained overproduction of eosinophils and a predilection to damage specific organs. There are several diagnostic criteria. First, the patient must sustained blood eosinophilia of greater than 1,500/mm3, for longer than 6 months. Secondly, other apparent etiologies for eosinophilia must be absent, ineluding parasitic infections and allergic diseases. Thirdly, the patient must have signs and symptoms of organ involvement. Cardiac and neurologic diseases, frequent in HES, are major causes of morbidity and mortality. The damage to the heart and nervous system is due to thrombosis and fibrosis. Gastrointestinal tract involvement can accompany HES, but severe eosinophilic colitis was very rarely described in association with this syndrome. In this report, we present a patient with HES and eosinophilic colitis who was successfully treated with steroids. (Korean J Gastrointest Endosc 18: 417-423, 1998)
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